Center for Human Genetics and Laboratory Diagnostics, Dr. Klein, Dr. Rost and Colleagues

Hepatitis A Virus (HAV)

Dr. med. Hartmut Campe, Dr. med. Hanns-Georg Klein

Scientific Background

Hepatitis A Virus (HAV) infection is usually transmitted by contaminated food and touch. It is a typical infection contracted whilst traveling and can lead to outbreaks in communal facilities and sporadic clusters of disease caused by the consumption of contaminated food (see literature). Although infection in early childhood is usually asymptomatic, it leads to acute hepatitis (jaundice) in adults, which is seldom fulminant. Chronic infection patterns are not expected in patients with healthy immune systems. Lifelong immunity can be assumed following infection.

The best prevention is a hepatitis A vaccination.

HAV infection is diagnosed through serology.